Bone Abstracts

According to the literature data, some parameters of the femur (length of axis, length of femoral neck) are independent predictors of hip fractures, but such studies among Ukrainian patients are absent. The purpose of this study was to study age and gender features of some geometric parameters of the upper third of the hip in patients with intra- and extra-articular fractures of the femur.One hundred and seventy-four survey radiographs of the hip joints ...

Osteoarthritis is a complex pathogenesis because diverse factors interact causing a process of deterioration of the cartilage and the subchondral bone. Despite the multifactorial nature of the knee osteoarthritis, it is related to a strong genetic component. Determination of molecular genetic causes of osteoarthritis is an actual problem. There are several approaches to assess the contribution of a candidate gene in the pathogenesis of osteoarthritis. The aim of the study was ...

Osteoporosis has a complex etiology and is considered a multifactorial polygenic disease in which genetic determinants are modulated by hormonal, environmental, and nutritional factors.Polymorphism of the vitamin D receptor gene has been reported to play a major role in variations for genetic regulation of bone mass but its role within various ethnic populations is not clear. Estrogens are known to play an important role in regulating bone homeostasis, t...